Say it ain’t so! The co-star of Apple’s popular “Get a Mac” ads is claiming in a new interview that the commercials “might be done.”

Apple’s “Get a Mac” advertising campaign launched in 2006, the brainchild of TBWA\Media Arts Lab, Inc., who does most of the company’s campaigns. The popular ads always begin with laid-back, hip-looking actor Justin Long announcing, “Hello, I’m a Mac,” followed by button-down, nerdy-looking humorist John Hodgman proclaiming, “And I’m a PC” and then proceed to tout the reasons why the Mac is better than a PC.

But in a potential foreshadowing of things to come on the eve of Apple’s iPhone OS 4.0 preview today, actor Justin Long is saying that the company’s advertising campaign may have come to and end, according to The A.V. Club.

“You know, I think they might be done. In fact, I heard from John [Hodgman], I think they’re going to move on,” Long proclaims when asked about the current status of the Apple commercials.

“I can’t say definitively, which is sad, because not only am I going to miss doing them, but also working with John,” the actor concludes. “I’ve become very close with him, and he’s one of my dearest, greatest friends. It was so much fun to go do that job, because there’s not a lot to it for me. A lot of it is just keeping myself entertained between takes, and there’s no one I’d rather do it with than John.”

If true, it could signal a shift in direction for Apple -- with the iPhone and the iPod touch doing record business and now adding the iPad into the equation, it’s clear that iPhone OS is where it’s at.

While we can’t see Apple totally abandoning the Mac and OS X, people are clearly taking to this trio of iPhone OS devices, which are expected to gain even more powerful skills after today’s media event previewing the fourth generation of the software. Perhaps Apple knows something that we don’t -- could they be starting to abandon the idea of being chained to a desktop or even laptop in favor of a mobile computing revolution? Time will tell.