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I am looking for thoughts and opinions on the various JS frameworks.  That may sound pretty open-ended, but I am hoping to find more info beyond the what the sites claim.  I have googled some of them but they tend to be n00b devs discussing which is easier and such.  Nothing substansive.

I have used Prototype/Scriptaculous extensively and am very familiar with Mootools.  I am somewhat farmiliar with extJS.  I want to move away from Prototype/Scriptaculous (well mostly scriptaculous) because of the bulk it carries with it. 

But I am looking for a fast efficient base frame work that is extensible.  The goal is use it as more of a scaffolding than a direct framework.  Performance and memory usage a are big issues.  Not really interested in the admittadly cool features for class declarations and such that Moo/Proto have.  They are slick, but then you are tied to those frameworks. 

Again no specific question here, just thoughts. All thing like this have walls you hit when you venture past the basic functionality that 99% of people use.  We have hit several bugs and limitations with prototype that you really don't find discussed often because they are used mostly in a cookie cutter fashion.

TIA.