True Mac wizards keep their hands on the keys, and Apptivate can help, letting you assign hotkeys to open an application, file, folder, Automator script -- anything executable or openable. The menu bar app even blocks you if you're trying to use an established system-wide shortcut, like Command-C.
Tired of taking screenshots and having them clutter up your desktop? Want to instantly store the screenshots online and automatically copy the link to the clipboard? Sure you could do this manually, but a new tool called GrabBox hopes to save you some time and do this task automatically.